1) The Adkins selection roulette
With everything to gain, could Nigel afford to be bold and make some changes to his defence? With both Ferdinand and Hector now available for selection after injury and suspension respectively, could the manager decide to try a totally new centre half partnership? If so, it will be our fourth different pairing in central defence.
If Danny Williams returns to central midfield, this could potentially be our sixth different central midfield pairing of the season.
2) Rotherham's pressing game
One noticeable thing about previous Rotherham games has been high up the field they play. The Millers look to pen their opponents in their own half and their 44.3% of possession, the league's lowest, shows they are more than happy to go long if it gives them the chance to start a counter attack. With this in mind Jamie Mackie will surely return to the starting line-up, with his pace offering a potential threat for balls played behind Rotherham's high line by Oliver Norwood.
3) Pringle's crisp passing
A quick look at WhoScored's characteristics for both teams makes potentially worrying reading for Royals fans. One of Rotherham's strengths is creating scoring chances whilst Reading are weak at stopping opponents from creating chances. So expect the Millers to have chances tonight!
To do that Reading will have to keep an eye out for Ben Pringle. The 25 year old was linked with a move to the Madejski Stadium last season and it is easy to see why. The talented left midfielder has created 49 chances this season, 30 more than any of his team mates. Once again Chris Gunter, presuming he is picked, will be up against the opposition's most dangerous player, let's hope he has a better time than he did against Ben Marshall on Saturday.