Things got off to a rapid start at the Madejski as a shot from Pogrebnyak looks to have been hand-balled, but nothing was given.
The bright start was rewarded as a cross from the right hit Trippier and deflected into the net, giving the Royals the lead they had hoped for.
However, things were soon flipped upside down as Burnley scored twice through Arfield and Ings.
McCleary scored an absolute screamer in the second half, before the Royals piled on the pressure in an attempt to seal the win.
Burnley held firm and cleared a number of shots off the line.
Reading looked to have sealed their play-off spot right into the 90th minute, before Brighton sealed a last-minute 1-2 victory over Nottingham Forest, and snatched the coveted 6th spot from Reading in the cruelest manner possible.
Stay tuned to The Tilehurst End for a full match report, player ratings and 5 things in the coming days...