Pre-season form: LDWD
Tariqe Fosu could make a return for Royals after an ankle problem. Paul McShane could also feature, while striker Orlando Sa is expected to play some part having got 45 minutes against Crawley Town. Hal Robson-Kanu is expected to miss out, however, as will defender Jake Cooper.
Garath McCleary and Michael Hector will also no feature after recently returning from International duty with Jamaica.
Pre-season form: DWW
Espanyol finished 10th in La Liga last season and are managed by former Spain international midfielder Sergio. They will have to bounce back from losing two stand out players in goalkeeper Kiko Casilla who has moved to Real Madrid and striker Christhian Stuani who has joined Middlesbrough.
The 2006 Copa Del Rey winners, who also play Southampton on Sunday, have brought a 23-man squad for their two pre-season games in England.
Reading 1-2 Espanyol