Jon Dadi Bodvarsson vs Paul McShane
The Icelandic international who scored against Austria at Euro 2016 and on his debut for Wolves last weekend at Rotherham will be very much a player to keep an eye on.
Bodvarsson has some of the key elements that is required of a striker, with his height and his ability to find the back of the net when given the opportunity.
Looking to stop him will be Reading's main man in defence - Paul McShane. The centre back was very solid against Preston last week making some important clearances in the process.
If there is any player that can stop Bodvarsson from making an impact, it will be McShane and if he can do this then this will go a long way in Reading coming out on top.
Dave Edwards vs Danny Williams
Wolves captain Dave Edwards plays at the heart of the midfield three and will be looking to spearhead attacks for his side. Last season he got five goals and two assists for his side, as they finished 14th with 58 points.
It will be therefore Danny Williams' job to stop Edwards from dictating the play when Wolves have the ball, breaking play up and stop Edwards from linking up with Wolves' front three of James Henry, Bodvarsson and Jed Wallace.
If Williams can do this then this will be a huge gain for Reading, as they'll be stopping Wolves' main man in midfield from inflicting any damage to this Reading side.
Dominic Iorfa vs Roy Beerens
Young Englishman Dominic Iorfa will be another player that Reading fans travelling up should keep an eye on. Last season the right back helped keep 14 clean sheets in 42 league games for his side, including the two games against Reading.
Iorfa should be available having served a one match ban in Wolves' 2-1 win over Crawley in the EFL cup during midweek.
The 21 year old is in my view is one of the best young right backs in the championship, with his pace, his tackling and the ability to pull out the odd trick or two. He is the sort of player that loves to get forward and join the attacks, something that makes him a fans favourite at Wolves.
It will be interesting to see how Iorfa copes with Roy Beerens when Reading are on the attack, with his pace and his trickery. The Dutchman should also be full of confidence having produced an eye catching display against Preston and scoring his first goal in English football against Plymouth in midweek.
This will be a fascinating battle down the left hand side, as both players are good both defensively and offensively. If Beerens can win the battle against the Wolves right back, then it will go a long way in Reading hopefully getting the three points in their first away game of the 2016/17 season.