Liam Moore vs Clayton Donaldson
The Jamaican striker has been in good form recently with three goals in his last two games for the Blues. Last season Donaldson got 11 goals and 11 assists in 40 appearances, one of which came against Reading in their 2-0 win at the Madejski back in April.
Looking to stop him will be Liam Moore. The central defender has looked strong since joining in the summer, helping his side to back-to-back league wins without conceding from open play.
Moore will be the best person to deal with Donaldson, with the striker having the pace and height to cause any defence problems. Moore is also similar to Donaldson with his physicality, so he'll be the perfect man to deal with Donaldson.
The battle will also be a fascinating one with both players being 6ft 1in, so it will be interesting as to which player can win the headers for his team and dominate the air. Donaldson is also likely to be playing up front on his own tomorrow night, so Birmingham will depend on him to hold the ball up and spearhead attacks.
Chris Gunter vs Jacques Maghoma
The winger from DR Congo is Birmingham's main threat on the left. Last season Maghoma got five goals and two assists in 40 appearances as the Blues finished a respectable 10th.
Looking to keep him quiet down the left will be Chris Gunter; the defender has played every league game for the Royals this season and will be looking to put in a solid performance on Tuesday night.
Maghoma has already got one goal and an assist to his name so far this season, so Gunter will need to be on his toes in order to stop Maghoma from making an impact.
Yann Kermorgant vs Ryan Shotton
The centre back who was signed on a permanent deal from fellow Championship side Derby in the summer has played every game for the Blues so far this season, keeping two clean sheets.
It is worth noting that whilst on loan Shotton scored only one goal, against you name it - Reading - in their win at the Madjeski.
Shotton is set to battle with Yann Kermorgant. The Frenchman has scored only one goal so far this season, but Reading manager Jaap Stam has backed his striker to fire the goals in for the Royals.
Once again Kermorgant will be playing up front on his own, so the focus will be on a fascinating one-on-one duel with both players being over six foot tall and ready for a physical battle. Whoever wins this battle will go a long way into which side comes out on top.